MedChem Discovery Consulting

Medicinal Chemistry

MedChem Discovery Consulting offers medicinal chemistry consulting services for Lead Identification, Lead Optimization, Candidate Nomination and the preclinical phases of R&D. Experience includes structure-based drug design, fragment-based drug discovery, screening library design, privileged structures, lead-hopping, G-protein coupled receptor ligands, enzyme inhibitors and ion-channel ligands.

William J. Greenlee

Dr. William J. Greenlee is an experienced Medicinal Chemist, Research Director and Project Manager with a record of success in over three decades of research in industry (Merck Research Laboratories, Schering-Plough Research Institute). He provided leadership to research groups that advanced 20 drug candidates into preclinical development and 11 into clinical studies. He contributed to medicinal chemistry programs that have led to marketed drugs (Vasotec™, Prinivil™), and directed programs that contributed drug candidates now in clinical trials, including vorapaxar (thrombin receptor antagonist – Phase 3) and preladenant (adenosine A2A antagonist – Phase 3) and MK-8931 (beta-secretase inhibitor – Phase 1). Bill has demonstrated strong communication and team-building skills and has made contributions to the medicinal chemistry community that have been recognized by local and national awards.

Medicinal Chemistry

Due Diligence Services

William J. Greenlee